He studied architecture at IUAV in Venice where personalities such as Carlo Scarpa and Ernesto Nathan Rogers taught. He then attended the Institute of Industrial Design in Venice. In 1959 he joined N Group, which was born in Padua: 9 other artists participated with him including Alberto Biasi, Ennio Chiggio and Milena Vettore, that he met a few years earlier at the Venetian design institute. The group broke up in 1964. In 1972 he took part in the exhibition at the Museum of Modern Art in New York: “Italy: The New Domestic Landscape”. Since 1983 he has lived and worked in New York; in this city he founded Fish Design company. In 1996 a retrospective was dedicated to him at the Center Georges Pompidou, but his works are exhibited in other great museums around the world, including the Museum of Modern Art and the Metropolitan Museum of Art in New York and the Victoria and Albert Museum in London. Pesce is one of the greatest representatives of Italian design, in particular of radical design.